Puppy vaccination protocol using Zoetis vaccines

By Dr. Geoff Carullo, DVM, FPCCP, DPCVSCA

Why Choose Zoetis?

Zoetis’ Vanguard® vaccine line is one of the most trusted worldwide, offering comprehensive coverage for canine core and non-core diseases.

With Vanguard, you get strong immunogenicity, safe formulations, and the confidence of decades of use globally.

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Vaccination Schedule (3-week intervals)

Week 6

• Vanguard Plus 5/CV-L
  (Canine Distemper, Adenovirus Type 2, Parvovirus, Parainfluenza, Leptospira canicola and icterohaemorrhagiae, Canine Coronavirus)

Week 9

• Vanguard Plus 5/CV-L
  (repeat core + lepto + corona booster)

Week 12

• Vanguard Plus 5/CV-L
• Defensor 3 (Rabies)
  Note: This is the first rabies shot and required by law at 3 months.

Week 15

• Vanguard Plus 5/CV-L
  (final primary booster)
• Vanguard B (Kennel Cough: Bordetella bronchiseptica, injectable)

6 Months Old

• Booster with Vanguard Plus 5/CV-L
• Defensor 3
• Bronchine CAe

Yearly Boosters

• Defensor 3 (Rabies)
• Optional: Vanguard Plus 5/CV-L booster (if high exposure to Parvo/Lepto)
• Bronchicine CAe

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Does Canine Coronavirus Need a Booster?

If it’s already covered in the Vanguard Plus 5/CV-L series, no additional corona-specific booster is needed unless there’s a local outbreak. It is generally considered a non-core vaccine.

Summary Highlights:

• 3-week intervals: For effective immune priming
• Lepto included from 6 weeks
• Same brand consistency = enhanced immunogenic synergy
• Corona and Bordetella coverage for high-risk pups
• Tailored for Philippine canine practice realities

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Dr. Geoff Carullo is a Fellow and the current President of the Philippine College of Canine Practitioners.

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